New ideas for weight loss! Harvard University: Nanocellulose inhibits fat absorption

Issuing time:2021-03-30 14:38

朗邦营养

朗邦营养

Food is accompanied by fat, which people love and hate! Lipids of the same mass release twice as much energy as carbohydrates. Too much lipid will be converted into body fat, which is stored in the body's fat cells, thus causing obesity!


New ideas for weight loss! Harvard University: Nano dietary fiber inhibits the digestion and absorption of fat. The addition of nanocellulose to foods reduces the digestion and absorption of fat. The work of DeLoid et al. at Harvard University was recently published in the journal ACS Nano (IF=13.709).


Nanocellulose Fibers

Nanocellulose fibers are fibers that deaggregate crystalline cellulose into nanoscale by physical, chemical, or biological methods.

Compared with traditional powder cellulose, NFC has a large specific surface area, strong spatial expansion, and surface hydroxyl group activation, which can be used as an excellent new dietary fiber.


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Model diagram simulating small intestinal digestion





Nanocellulose inhibits the mechanism of digestion and absorption of fat:

The physical binding of nano-dietary cellulose to food fats interferes with the activity of pancreatic lipase, reducing the digestion and absorption of fats.

                                                                                                                                              0.785%-1%(w/w)The amount added reduces the intake of fatty foods 36%-52%的Fat digestion.



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By adsorbing fat, reducing the contact area of small intestinal lipase to form steric hindrance, and reducing the emulsification of bile salts, nano-fiber nano-lipid composite structure (nanofiber trunk, linking fixed fat particles), avoiding digestion and lipase hydrolysis.

         

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It forms a dendritic nanoscale fiber-oil composite structure to avoid digestion and lipase hydrolysis





Mouse experiments

Effect of nanocellulose on serum TG changes after gavage in rats. Nanocellulose can inhibit the digestion and absorption of fat and control the concentration of triglycerides in serum after meals.


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White kidney bean dietary fiber

White kidney bean dietary fiber is a fiber with a nanostructure. White kidney bean dietary fiber is selected from high-quality white kidney beans, and resistant starch and insoluble dietary fiber are extracted by biological enzymatic hydrolysis process, which gives white kidney bean dietary fiber more functionality through biological modification and purification.

Nanoscale cellulose-----Compared with general dietary fiber, the unique nanostructure of white kidney bean dietary fiber has greater specific surface area, accessibility and surface activity;

Biomodified hydrophobic groups------Through biomodification, white kidney bean dietary fiber has a strong ability to adsorb oil and bile salts in a water-oil mixing system



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White kidney bean dietary fiber is jointly developed by the Sino-US joint laboratory composed of Jiangnan University, the University of Georgia and Cornell University, and this technology has obtained a US patent (patent number: US 9,149,064 B2). The special structure of white kidney bean dietary fiber makes it unique.


                                                                                                                                                                                                                                                               

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All are dietary fiber, not all dietary fiber can absorb oil. The lipophilic properties of white kidney bean dietary fiber have a lot to do with its structure.


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